Guanosine Pentaphosphate

Guanosine 5'-triphosphate 2'(3')-diphosphate. A guanine nucleotide containing five phosphate groups. Three phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids are not available for protein synthesis.

Also Known As:

Guanosine 3'-Diphosphate 5'-Triphosphate; 3'-Diphosphate 5'-Triphosphate, Guanosine; 5'-Triphosphate, Guanosine 3'-Diphosphate; Guanosine 3' Diphosphate 5' Triphosphate; Pentaphosphate, Guanosine; pppGpp, Alarmone; (p)ppGpp; Alarmone; Alarmone pppGpp; Bacterial Magic Spot pppGpp; ppprGpp; Guanosine 5'-(tetrahydrogen triphosphate), 3'-(trihydrogen diphosphate)

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleotides: 140
        Guanine Nucleotides: 675
        Guanosine Pentaphosphate: 195
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Ribonucleotides: 307
    - Guanine Nucleotides: 675
      - Guanosine Pentaphosphate: 195
  - Purine Nucleotides: 140
    - Guanine Nucleotides: 675
      - Guanosine Pentaphosphate: 195

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Disease

Drug/Important Bio-Agent (IBA)